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Premarin is a mixture of estrogen hormones which regulates development and functions of female reproductive system, formation of female secondary sex characteristics. On entering into the bloodstream it forms a complex with a specific receptor (in the fallopian tubes, cervix, excretory ducts of the mammary glands, vagina, urethra, breast, liver, hypothalamus, hypophisis), stimulates synthesis of DNA and proteins. It results in proliferation of the epithelium, increased sensitivity of the uterus and tubes muscles of to medications stimulatign their motility. This medication decreases bone resorption of Ca2 + in menopause, prevents involution of the genitals. Premarin is used to treat symptoms of menopause which include hot flashes, vaginal dryness, vaginal irritation and dryness, to prevent osteoporosis in postmenopausal women. Replacement therapy in peri- and postmenopausal women, ovarian hypofunction (primary and secondary amenorrhea, oligomenorrhea, dysmenorrhea) and other conditions.
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Premarin is a mixture of estrogen hormones which regulates development and functions of female reproductive system, formation of female secondary sex characteristics. On entering into the bloodstream it forms a complex with a specific receptor (in the fallopian tubes, cervix, excretory ducts of the mammary glands, vagina, urethra, breast, liver, hypothalamus, hypophisis), stimulates synthesis of DNA and proteins. It results in proliferation of the epithelium, increased sensitivity of the uterus and tubes muscles of to medications stimulatign their motility. This medication decreases bone resorption of Ca2 + in menopause, prevents involution of the genitals. Premarin is used to treat symptoms of menopause which include hot flashes, vaginal dryness, vaginal irritation and dryness, to prevent osteoporosis in postmenopausal women. Replacement therapy in peri- and postmenopausal women, ovarian hypofunction (primary and secondary amenorrhea, oligomenorrhea, dysmenorrhea) and other conditions.
Estrogens stimulate the liver's ability to produce factors that promote the clotting of blood. Thus, concomitant administration of Premarin and warfarin (blood thinner) may cause decrease their effects. Barbiturates, Rifampin (Rifadin), phenytoin (Dilantin), carbamazepine (Tegretol), griseofulvin (Grifulvin), St. John's wort and primidone increase metabolism of estrogens. Erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), and ritonavir (Norvir) act oppositely.
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Hypersensitivity, pregnancy, breastfeeding, estrogen depending malignant tumors, undiagnosed genital or uterine bleeding, thrombophlebitis or thromboembolic disease in active phase (excluding treatment of breast and prostate cancers). Cautiousness should be exercised in patients with thrombophlebitis, thrombosis or thromboembolism (while taking estrogens in history); family hyperlipoproteinemia, pancreatitis, endometriosis, gallbladder disease in history (especially cholelithiasis), severe liver failure, jaundice (including one during pregnancy in history), hepatic porphyria, leiomyoma, hypercalcemia associated with bone metastases caused by breast cancer, underactive thyroid, porphyria, endometriosis, asthma.
Take the missed dose as soon as you remember about it. If it is almost time of your next dose just skip it and return to your regular schedule.
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Precautions
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Estrogens stimulate the liver's ability to produce factors that promote the clotting of blood. Thus, concomitant administration of Premarin and warfarin (blood thinner) may cause decrease their effects. Barbiturates, Rifampin (Rifadin), phenytoin (Dilantin), carbamazepine (Tegretol), griseofulvin (Grifulvin), St. John's wort and primidone increase metabolism of estrogens. Erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), and ritonavir (Norvir) act oppositely.
Premarin should be stored at room temperature, between 15-30 C (59-86 F). The right temperature to store the injection is between 2-8 C (36-46 F).
Possible side effect
Premarin is a mixture of estrogen hormones which regulates development and functions of female reproductive system, formation of female secondary sex characteristics. On entering into the bloodstream it forms a complex with a specific receptor (in the fallopian tubes, cervix, excretory ducts of the mammary glands, vagina, urethra, breast, liver, hypothalamus, hypophisis), stimulates synthesis of DNA and proteins. It results in proliferation of the epithelium, increased sensitivity of the uterus and tubes muscles of to medications stimulatign their motility. This medication decreases bone resorption of Ca2 + in menopause, prevents involution of the genitals. Premarin is used to treat symptoms of menopause which include hot flashes, vaginal dryness, vaginal irritation and dryness, to prevent osteoporosis in postmenopausal women. Replacement therapy in peri- and postmenopausal women, ovarian hypofunction (primary and secondary amenorrhea, oligomenorrhea, dysmenorrhea) and other conditions.
You may experience symptoms of allergy (hives, rash, swelling face and tongue) and also chest pain or heavy feeling, sudden numbness or weakness, abnormal vaginal bleeding, migraine headache, confusion, jaundice, swelling in hands, ankles, or feet. If such symptoms are severe stop taking this medication and notify your doctor at once.
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